Quick Answer
Most autoimmune conditions defer
Can You Donate Plasma With Autoimmune Disease?
Most autoimmune diseases disqualify you from plasma donation in 2026. Key reasons:
- Plasma quality: Autoantibodies affect plasma
- Medications: Many treatments disqualify
- Donor health: Donation may worsen symptoms
- Recipient safety: Protecting plasma recipients
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Common Autoimmune Conditions
| Condition | Can Donate? | Notes |
|---|---|---|
| Lupus (SLE) | Usually NO | Permanent deferral typical |
| Rheumatoid Arthritis | Usually NO | Especially if on biologics |
| Multiple Sclerosis | Usually NO | Permanent deferral typical |
| Crohn's Disease | Usually NO | IBD typically defers |
| Ulcerative Colitis | Usually NO | IBD typically defers |
| Psoriasis (mild) | MAYBE | If not on biologics |
| Psoriatic Arthritis | Usually NO | Especially on treatment |
| Hashimoto's | MAYBE | If stable on thyroid meds |
| Graves' Disease | MAYBE | If treated/stable |
| Type 1 Diabetes | Usually NO | Insulin-dependent |
| Celiac Disease | MAYBE | If managed with diet |
Autoimmune Medications That Defer
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Get the Pro Toolkit — $19Many autoimmune treatments disqualify donation:
Biologics (Usually Permanent Deferral)
- Humira (adalimumab)
- Enbrel (etanercept)
- Remicade (infliximab)
- Stelara (ustekinumab)
- Cosentyx (secukinumab)
- Rituxan (rituximab)
Immunosuppressants
- Methotrexate
- Azathioprine (Imuran)
- Mycophenolate (CellCept)
- Cyclosporine
Why Autoimmune Diseases Disqualify
The restrictions exist for important reasons:
- Autoantibodies: Your plasma contains antibodies that attack your own body - could affect recipients
- Plasma quality: Autoimmune processes change plasma composition
- Medications: Many treatments can't be in donated plasma
- Your health: Donation stresses the immune system
Exceptions and Alternatives
Possible Exceptions
Some milder autoimmune conditions may allow donation:
- Mild psoriasis: If topical treatment only
- Hashimoto's: If stable on levothyroxine
- Celiac: If diet-controlled
- Stable thyroid conditions: Well-managed may qualify
Alternative Ways to Help
If you can't donate plasma:
- Clinical trials: Research studies for your condition
- Advocacy: Support autoimmune organizations
- Fundraising: Help raise awareness
- Volunteer: Non-donation healthcare support
Frequently Asked Questions
I have mild autoimmune symptoms but no diagnosis - can I donate?
If you have symptoms but no formal diagnosis, be honest during screening. Undiagnosed autoimmune symptoms may still affect eligibility.
What if my autoimmune disease is in remission?
Even in remission, most autoimmune conditions still disqualify. The underlying condition and treatments usually matter more than current symptom status.
I only have thyroid antibodies - can I donate?
Hashimoto's or Graves' patients who are stable on medication (like levothyroxine) may be eligible. Check with your specific center.
Not Sure About Your Condition?
Contact centers directly to ask about specific conditions
Find Centers Near YouAlways disclose autoimmune conditions and medications during screening. Policies vary by center.
This is just one piece of the puzzle. For everything you need to know about plasma donation in 2026—earnings, centers, eligibility, and pro tips—check out our comprehensive resource: