Quick Answer
PCOS doesn't disqualify you
Can You Donate Plasma With PCOS?
Yes, PCOS doesn't disqualify you from plasma donation in 2026:
- Hormonal condition: Doesn't affect plasma quality
- Most medications OK: Birth control, metformin accepted
- Not autoimmune: Different from conditions that disqualify
- Common condition: Millions with PCOS donate regularly
PCOS Medications
| Medication | Can Donate? | Use |
|---|---|---|
| Birth control pills | YES | Hormone regulation |
| Metformin | YES | Insulin resistance |
| Spironolactone | Usually YES | Anti-androgen |
| Clomid (clomiphene) | Usually YES | Fertility treatment |
| Letrozole | Usually YES | Fertility treatment |
| Inositol | YES | Supplement |
| Ovasitol | YES | Supplement |
Why PCOS Doesn't Disqualify
- Hormonal syndrome: Affects ovaries and hormones, not blood
- Not contagious: Can't be transmitted through plasma
- Metabolic condition: Similar to other metabolic issues that are OK
- Medications acceptable: Most PCOS treatments don't affect plasma
PCOS Considerations for Donors
Iron Levels
Some PCOS patients may have considerations:
- Heavy periods: May lower iron levels
- Irregular periods: Can affect hydration timing
- Check hemoglobin: Must meet minimum levels
- Iron supplements: May help if levels are low
Insulin Resistance
Many with PCOS have insulin resistance:
- Metformin users: Can still donate
- Blood sugar: Eat before donating
- Not diabetic: IR alone doesn't disqualify
- Stay hydrated: Important for everyone
Tips for PCOS Donors
- Track your cycle: Know when you feel best
- Iron-rich diet: Especially if you have heavy periods
- Eat protein: Helps with blood sugar stability
- Stay hydrated: Always important
- Disclose medications: Be honest during screening
- Don't donate during flares: If you feel unwell, reschedule
Birth Control and Donation
Birth control pills are commonly used for PCOS:
- All types accepted: Combination, progestin-only
- NuvaRing/patch: Also OK
- IUDs: No impact on donation
- Depo shot: Accepted
Frequently Asked Questions
I take metformin for PCOS - can I donate?
Yes, metformin is generally acceptable for plasma donation. It's one of the most common medications for PCOS and insulin resistance and doesn't affect plasma quality.
My periods are very heavy - will I fail the iron test?
Heavy periods can lower iron/hemoglobin levels, which could cause you to be deferred. If you have heavy periods, consider donating mid-cycle when iron levels may be higher, and eat iron-rich foods regularly.
I'm currently doing fertility treatments - can I donate?
Most fertility medications like Clomid and Letrozole are acceptable. However, if you're undergoing IVF with hormone injections, you may want to pause donations. Check with your fertility doctor and the plasma center.
Does donating plasma affect my PCOS symptoms?
Plasma donation shouldn't affect your PCOS symptoms directly. However, staying well-hydrated and eating properly before and after donation is important for everyone, especially those managing metabolic conditions.
PCOS is one of the most common hormonal conditions in women and doesn't prevent plasma donation. Keep your health managed and you should have no issues!
This is just one piece of the puzzle. For everything you need to know about plasma donation in 2026—earnings, centers, eligibility, and pro tips—check out our comprehensive resource: