Plasma Donation Taxes 2026: Complete IRS Guide

Yes, plasma donation income is taxable. The IRS considers compensation for plasma donation as taxable income, regardless of whether you receive a 1099 form. This comprehensive guide explains exactly how to handle plasma taxes for 2026.

Is Plasma Donation Income Taxable?

Yes, absolutely. Despite what you may have heard, the IRS clearly considers plasma donation compensation as taxable income. Here's why:

• It's not a "donation" - You're being compensated for your time, not donating for free
• It's classified as "other income" - Reported on Schedule 1 of your tax return
• All amounts are taxable - Even if under $600 and no 1099 received

1099 Rules for Plasma Donation

You'll receive a 1099-NEC or 1099-MISC if you earned $600 or more from a single plasma center in a calendar year.

Important 1099 Facts

What If You Don't Get a 1099?

If you earned less than $600 at a center, or if the center failed to send a 1099, you're still required to report the income. Keep your own records:

• Save all payment receipts and statements
• Track donations in a spreadsheet
• Screenshot your center app earnings history

How to Report Plasma Income on Your Taxes

Step-by-Step Instructions

1. Gather your 1099s from each plasma center
2. Add up total earnings from all centers
3. Report on Schedule 1 (Form 1040), Line 8z as "Other Income"
4. Write "Plasma Donation" as the description
5. Calculate deductions (see below)

Deductions You Can Claim

You can reduce your taxable plasma income by deducting legitimate expenses:

Common Plasma Donation Deductions

Mileage Deduction Example

If your plasma center is 10 miles away:

• Round trip: 20 miles
• 8 donations/month × 12 months = 96 donations
• 96 × 20 miles = 1,920 miles/year
• Deduction: 1,920 × $0.70 = $1,344

Do You Need to Make Estimated Tax Payments?

If you expect to owe $1,000 or more in taxes from plasma income, you may need to make quarterly estimated tax payments to avoid penalties.

2026 Estimated Tax Due Dates

How Much to Pay

Set aside approximately 15-25% of your plasma earnings for taxes, depending on your tax bracket. A simple formula:

• Lower income: Set aside 15%
• Middle income: Set aside 20%
• Higher income: Set aside 25%

State Tax Considerations

In addition to federal taxes, most states tax plasma income. Here's what to know:

States With No Income Tax (Plasma is Tax-Free)

• Alaska
• Florida
• Nevada
• South Dakota
• Tennessee (no wage tax)
• Texas
• Washington
• Wyoming

All Other States

You'll owe state income tax on plasma earnings. Rates vary from 1% to 13% depending on your state and income level.

Common Plasma Tax Mistakes to Avoid

1. Not reporting income under $600 - It's still taxable even without a 1099
2. Forgetting mileage deductions - This can save you hundreds
3. Not keeping records - Track all donations and payments
4. Ignoring estimated taxes - Can result in penalties
5. Claiming it as a charitable donation - It's not; you were paid

Plasma Tax Calculator

Use this quick formula to estimate your plasma taxes: